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GOP presidential hopeful Rick Santorum released what may be the hardest-hitting ad of the 2012 campaign. "Welcome to Obamaville," shot and scored like a trailer for a Hollywood horror film, features a split-second flash of President Obama's face superimposed over the image of Iranian President Mahmoud Ahmadinejad. Guest host Laura Sullivan speaks to NPR's David Folkenflik about the ad.

Louisiana holds its Republican primary Saturday. Guest host Laura Sullivan talks with NPR's Don Gonyea about the state of play in the race for the GOP presidential nomination.

Every year, thousands of migrants cross the border from Mexico to Arizona, leaving behind artifacts from their journeys. Some of the items end up in trash bags, others in a museum. Still others end up in the morgue.

Dick Cheney, 71, was in a Virginia hospital following a heart transplant Saturday. Host Laura Sullivan talks with NPR's Rob Stein about the former vice president's health.

Pope Benedict XVI's trip will be the first papal visit to the island since John Paul II's historic trip in 1998. Two outdoor public Masses will give Benedict a chance to address the Cuban people, and all sides of Cuba's long political conflict will be looking for a little sympathy from the pope.

Members of the National Guard's 182nd Infantry Regiment recently touched down in Indiana after a long trip and a long year in Afghanistan. Over the next year, Weekend Edition will follow these men through their shift from soldiers to civilians.

Artyom Savelyev's adoptive mother in Tennessee put him on a plane two years ago and sent him back to his homeland, unaccompanied. Now, he's living with a foster mother near Moscow. The 9-year-old's journey highlights the challenges both within Russia and between Russia and the U.S. over how to care for orphans.

While most states are scrambling to comply with the Affordable Care Act, Florida has a different, high-stakes strategy. Republican leaders are betting that the Supreme Court will strike down the law, and have rejected and returned federal grants to help develop a health care exchange.

Can the government force you to buy health insurance? We examine the issues at stake each day as the Supreme Court hears oral arguments over President Obama's health care overhaul.

President Obama is in South Korea Sunday to take part in a multilateral conference aimed at curbing nuclear proliferation. He arrives in South Korea at a time of considerable tension. North Korea is threatening to carry out a long-range rocket launch in April, an action the U.S. has warned it should not take.