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Has this craze officially "jumped the shark?" With word that up to 4,000 such videos are uploaded every day, that some people are losing their jobs because of them and that The Simpsons has now added its version, it just may have.

More than 90 clinical trials have tested therapeutic vaccines in cancer patients, but the results have been a mixed bag. A recent study in mice suggests that changing a traditional ingredient in the vaccines could make a big difference.

Telecommuting is quickly becoming a new normal for the workplace. So why has tech giant, Yahoo, decided to nix it? Host Michel Martin explores whether staying in the office will help the faltering company stay in the game.

Lawmakers failed to avert across-the-board spending cuts to the federal government, and they officially kicked in last week. Host Michel Martin speaks with NPR senior business editor Marilyn Geewax, and The Wall Street Journal's Sudeep Reddy about what it all really means.

The wealth gap between white and black families is growing — and that's especially apparent in the housing market. Host Michel Martin talks to Washington Post correspondent Michael Fletcher about the financial disparities facing black families.

The rodents have been a big problem in Iran's capital for years. Efforts to poison them may have run their course. So, according to local reports, sniper teams have been deployed. Some of their targets are quite large — weighing about 11 pounds.

President Obama rounds out his Cabinet for his second term, nominating three new leaders Monday: Walmart Foundation's Sylvia Mathews Burwell for budget chief, MIT scientist Ernest Moniz to head the Energy Department and veteran regulator Gina McCarthy to run the EPA — a post that's likely be a lightning rod during Senate confirmations.

On the HBO series Enlightened, a naive corporate executive played by Laura Dern wants to change the world. The series' creator and writer, Mike White, says the show's whistle-blowing plot line was inspired, in part, by his own father's experience.

A photographer peers into the past — and into old suitcases from an abandoned asylum.

With at least $14 billion in long-term liabilities and $327 million in debt, Detroit has declared a financial emergency. Several cities have tried this approach before, and the results have been mixed.