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For the first time, a top Russian diplomat has said that the Syrian president may be toppled. Coming from a country that has been among Assad's strongest supporters, the words are significant, analysts say.

Fifty-five percent of those surveyed said President Obama is making a "serious effort" to work with Republicans. Just 32 percent said Republicans are making a serious effort to work with the Democratic president.

Maysoon Zayid is a Palestinian Muslim with cerebral palsy. She's turned that identity into a tool for laughter, performing stand-up around the world. She says she doesn't apologize to anyone for her very political and personal jokes. Host Michel Martin talks to Zayid about her comedy and a program she runs in the West Bank.

Nearly a third of pedestrians crossing some of Seattle's most dangerous intersections were doing something distracting at the same time. People texting were four times more likely to cross the street without looking both ways.

Some places have banned fracking, a controversial type of natural gas drilling. Critics say the process contaminates groundwater. But proponents say it creates jobs and energy independence. Host Michel Martin is joined by NPR's Jeff Brady and reporter Scott Detrow from NPR's StateImpact project in Pennsylvania. They discuss the boom and bust of fracking.

In 2013 and 2014, there will be a number of substantial realignments in the NCAA conferences. Some believe that the realignment process will ultimately result in the creation of four "super conferences." NPR's Mike Pesca talks about how conference shifts could effect the future of college athletics.

A fresh look at what makes people sick around the world finds that life expectancy has ticked up in the past 20 years. But people aren't necessarily in the best of health during those extra years. Chronic problems, like depression and pain, are on the rise.

The United States is facing its worst drought since the 1950s, according to the National Oceanic and Atmospheric Administration. With little to no signs of relief on the horizon, many analysts expect conditions to worsen well into next year.

Legos often cost twice as much as similar blocks from a rival toymaker. So why are Legos so much more popular than other brands?