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NASA's Artemis II mission lifted off from Kennedy Space Center in Florida at 6:35 p.m. Eastern Wednesday. The mission aims to send four astronauts around the moon on a roughly 10-day journey.

A UC Santa Cruz student film showcase on May 29 at 6 p.m. will highlight the experiences of people who have been wrongfully convicted of crimes. And, state lawmakers make progress toward regulating AI in workplaces.

Beijing says it will test all 3.6 million residents in its largest district after finding about four dozen COVID cases. Residents fear a city-wide lockdown is imminent.

Mitt Romney swept all five primaries on Tuesday, solidifying his hold on the GOP presidential nomination. Newt Gingrich made a last stand in Delaware, but came up short and aides to the former House speaker say he plans to suspend his campaign soon and will likely endorse Romney.

Presidential debates can provide a boost to a candidate, thwart a lead in polls or prompt a decision to leave the race. NPR's Ken Rudin and Alan Schroeder, author of Presidential Debates: 40 Years of High-Risk TV, look at game-changing moments in the 2012 election cycle.

The investigation continues. The FBI and other agencies are appealing to the public for help. It's possible the key clue may be in a photo or video taken by a spectator.

The president visited U.S. forces who are part of the fight against ISIS, amid criticism of a sudden decision to pull troops from Syria. It's his first such trip since taking office.

The budget process allows the party in control in Congress to pass most big-dollar legislation without having to worry about a filibuster. But the process can be risky.

The last four U.S. presidents have found themselves mired in Afghanistan. The last two saw the war as an unwanted inheritance and an albatross, and they were determined to end the American role.

The Bob's Burgers Movie, Jordan Peele's Nope, and Fire Island with Bowen Yang and Joel Kim Booster are all on our critics' lists.